Figure 2.

Graphical representation of exemplar overlapping and spurious proteins. (a) shows two proteins from the Corynebacterium efficiens genome that encode components of a restriction system. The C-termini of the two proteins overlap by 97 nt. (b) Two highly overlapping predicted proteins from the Rhodopirellula baltica genome coded on opposite strands of DNA. The Q7UY10 protein contains two Pfam DUF1596 domains. There is no evidence that these are true expressed proteins. Green boxes represent regions matched by Pfam families, the red shaded areas represent transmembrane domains predicted by Phobius (10) and the blue shaded areas represent regions of low complexity (11).