Figure 1.
(A) Structural modification of MSNB's leading to SNPT's. (B) The translucent shape is the van der Waals surface of MSNB's and SNPT's. The colors of translucent represent electrostatics of both molecules; red (negative), blue (positive), and white (neutral). Overall there is good alignment between the MSNB's and the SNPT's thus indicating their theoretical viability as more stable bioisosteres.