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. Author manuscript; available in PMC: 2013 Mar 7.
Published in final edited form as: J Med Chem. 2012 Feb 23;55(5):2301–2310. doi: 10.1021/jm201546m

Figure 1.

Figure 1

(A) Structural modification of MSNB's leading to SNPT's. (B) The translucent shape is the van der Waals surface of MSNB's and SNPT's. The colors of translucent represent electrostatics of both molecules; red (negative), blue (positive), and white (neutral). Overall there is good alignment between the MSNB's and the SNPT's thus indicating their theoretical viability as more stable bioisosteres.