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. 2012 Apr;13(2):86–94. doi: 10.2174/138920212799860670

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©2012 Bentham Science Publishers

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. (3). VLR gene assembly in lamprey lymphocytes. — The incomplete germline VLR genes are flanked by hundreds of LRR cassettes. The noncoding intervening sequence of germline VLR is replaced by LRR fragments that are sequentially copied from the flanking LRR cassettes. Mature complete VLR genes are assembled from either the LRRNT or LRRCT end in a stepwise fashion that is directed by short sequence homology between the donor and recipient LRR sequences. This figure was modified from [6].