Fig. (3).
Top Panel: Genomic architecture of miRNA-650-bearing Vλ genes in the human Ig-λ locus. The numbers the diagram indicate the positions of miR-650-bearing Vλ genes. Short vertical lines indicate Vλ genes, whereas long vertical lines indicate either Ig-λ constant genes (solid line) or joining genes (dotted line). Lower Panel: Schematic diagram of the overlap of miR-650 gene and the leader exon of Vλ gene is shown in a representative miR-650-bearing Vλ gene. Numbers correspond to the position of miR-650 gene and the positions of octamer, TATA box, leader exon, V-exon, and recombination signal sequence (RSS).