Skip to main content
. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Bioorg Med Chem Lett. 2012 Jan 21;22(5):2105–2109. doi: 10.1016/j.bmcl.2011.12.141

Figure 2.

Figure 2

Inhibition of R1881-induced AR translocation to the nucleus. LNCaP cells were grown on cover slips and then were treated with DMSO, bic (10 μM) or 5b (10 μM) for 3 hr, followed by treatment with R1881 (0.5 nM) for 3 hr. Fluorescence images show nuclear DNA (blue color) or AR protein (green color) in LNCaP cells. Nuclear-to-cytoplasmic AR ratio was measured using Openlab software.