Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Mar 19;196(6):727–742. doi: 10.1083/jcb.201107096

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2012 Ryan et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 1. — GO enrichment map of biological processes altered in prephenotype dt^27J mice. mRNA expression profiling of P4 WT (n = 3) and dt^27J (n = 3) DRGs. Genes were clustered based on GO term, and an enrichment map of those biological processes up-regulated (left) or down-regulated (right) in prephenotype dt^27J DRGs relative to WT littermates is depicted. Each node represents one GO term. The node size represents the number of genes clustered to each GO term, node color reflects the significance of the enrichment above the background of the entire mouse genome (white shows most significant, and black shows least significant; significance cut is P < 0.05, Fisher’s exact test), and edge length reflects the similarity between GO terms. Clusters of functionally related gene sets were manually circled and assigned a label representative of the overall biological process. The most significantly down-regulated biological process in prephenotype dt^27J DRGs is transport.