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. 2012 Mar;9(1):38–43. doi: 10.1089/zeb.2011.0705

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Copyright 2012, Mary Ann Liebert, Inc.

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FIG. 2. — Formation of the fibrotic reticulum. Representative images of the IPF and HLF grafts localized to the head and trunk regions of the 1 and 2 dpf host embryos. Left panel: Fluorescence: High cell motility is characteristic of the IPF grafts in 2 dpf embryos. Arrows pointing at the processes, wedge indicating the graft margin, * marking the foci. Yolk autofluorescence (background) and no signal in head and trunk regions in embryos without grafts (CON). Right panel: Brightfield images showing graft-related malformations in the head (unilateral anophthalmia and microphthalmia) and trunk (lump, axial deformities) regions in the graft-bearing embryo, and no deformities in embryos without grafts (CON); e, eye; ov, otic vesicle; p, pericardium; Y, yolk sack. Lateral view. Scale bar: 250 μm.