FIGURE 1.

Tertiary structure of the HR domain of OutC. A, schematic representation of the domain organization of inner membrane subcomplex component OutC and secretin OutD. B, assignment of the ¹H-¹⁵N HSQC spectra for the HR domain. C, sausage representation of the best 20 calculated OutC-HRF3 structures. The secondary structure is shown in color: α-helical residues are in red, and the β-sheet is in cyan. The diameter of the sausage reflects the dynamics of the protein in solution, which is plotted according to the residue α-carbon T2 relaxation profile.