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. 2012 Mar 7;205(8):1203–1213. doi: 10.1093/infdis/jis102

Figure 3.

Figure 3.

Postnecropsy pathology data from the 2 groups of nonhuman primates (NHPs). The percentage of lung area with tuberculosis-related pathology was estimated in both groups of NHPs (A) using methods described elsewhere [23, 25]. The x-axis values represent week postinfection. Red circles denote NHPs infected with Mycobacterium tuberculosis (Mtb), whereas blue circles denote NHPs infected with the Mtb:Δ-sigH mutant. Lines correspond to mean values. The differences between 2 groups were statistically significant. Gross pathology is shown for 3 representative NHPs each, infected with Mtb (top panel) and Mtb:Δ-sigH (bottom panel) (B). Histopathologic analysis of hematoxylin and eosin–stained lung samples from 1 representative NHP each, infected with Mtb (top panel) and Mtb:Δ-sigH (bottom panel) (C).