Table 2.
Association Between Helicobacter pylori and Glycated Hemoglobin
| Adjusted Mean Glycated Hemoglobin (%) |
||||||
| Subject Status | Overall |
Excluding Diabetes and Insulin Users |
||||
| H. pylori/BMI Status | No. of Subjects | Mean (SD)a | P Value | No. of Subjects | Mean (SD)a | P Value |
| NHANES 1999–2000 | ||||||
| Overall | ||||||
| – | 3669 | 5.40 (0.03) | 3514 | 5.22 (0.01) | ||
| + | 2403 | 5.49 (0.04) | .02 | 2173 | 5.29 (0.02) | .02 |
| Age <18 | ||||||
| – | 1146 | 5.11 (0.01) | 1143 | 5.09 (0.01) | ||
| + | 376 | 5.09 (0.02) | .40 | 376 | 5.09 (0.02) | .87 |
| Age ≥18 | ||||||
| – | 2523 | 5.38 (0.03) | 2371 | 5.29 (0.02) | ||
| + | 2027 | 5.60 (0.04) | .01 | 1797 | 5.36 (0.02) | <.01 |
| P value for interaction | <.01 | <.01 | ||||
| Age ≥18, BMI <25 | ||||||
| – | 939 | 5.33 (0.04) | 909 | 5.17 (0.02) | ||
| + | 627 | 5.31 (0.06) | .73 | 593 | 5.17 (0.02) | .79 |
| Age ≥18, BMI ≥25 | ||||||
| – | 1584 | 5.63 (0.04) | 1462 | 5.37 (0.03) | ||
| + | 1400 | 5.79 (0.05) | <.01 | 1204 | 5.48 (0.04) | <.01 |
| P value for interaction | <0.01 | <0.01 | ||||
| NHANES III | ||||||
| Overall | ||||||
| – | 3260 | 5.47 (0.02) | 3069 | 5.28 (0.01) | ||
| + | 4157 | 5.50 (0.02) | .08 | 3763 | 5.35 (0.01) | <.01 |
| BMI <25 | ||||||
| – | 1553 | 5.24 (0.02) | 1510 | 5.16 (0.02) | ||
| + | 1612 | 5.30 (0.02) | .03 | 1526 | 5.21 (0.02) | <.01 |
| BMI ≥25 | ||||||
| – | 1707 | 5.63 (0.03) | 1559 | 5.38 (0.02) | ||
| + | 2545 | 5.66 (0.03) | .35 | 2237 | 5.46 (0.02) | <.01 |
| P value for interaction | .04 | <.01 | ||||
Abbreviations: BMI, body mass index; NHANES, National Health and Nutrition Examination Survey.
a
Parameter estimates from linear regression were adjusted for age, sex, smoking status, educational attainment, ethnic background, and BMI (except for analyses stratified by BMI).