Table 3.
Association of Helicobacter pylori With Glycated Hemoglobin, in the National Health and Nutrition Examination Survey III
| Adjusted Mean Glycated Hemoglobin (%) |
|||||||
| Subject Status |
Overall |
Excluding Diabetes and Insulin Users |
|||||
| H. pylori/BMI Status | cagA | No. of Subjects | Mean (SD)a | P Value | No. of Subjects | Mean (SD)a | P Value |
| Overall | |||||||
| – | – | 3095 | 5.48 (0.02) | 2884 | 5.31 (0.01) | ||
| + | – | 1430 | 5.51 (0.04) | .32 | 1279 | 5.37 (0.02) | .01 |
| + | + | 2781 | 5.52 (0.03) | .02 | 2484 | 5.41 (0.02) | <.01 |
| BMI <25 | |||||||
| – | – | 1406 | 5.26 (0.02) | 1363 | 5.17 (0.02) | ||
| + | – | 552 | 5.34 (0.04) | .06 | 522 | 5.25 (0.03) | .01 |
| + | + | 1060 | 5.31 (0.03) | .05 | 1004 | 5.22 (0.02) | .03 |
| BMI ≥25 | |||||||
| – | – | 1667 | 5.64 (0.04) | 1521 | 5.39 (0.02) | ||
| + | – | 862 | 5.65 (0.04) | .88 | 757 | 5.43 (0.03) | .24 |
| + | + | 1683 | 5.68 (0.04) | .13 | 1480 | 5.49 (0.03) | <.01 |
| P for interaction of H. pylori+/cagA− and BMI | .64 | .39 | |||||
| P for interaction of cagA+ and BMI | .02 | <.01 | |||||
Abbreviation: BMI, body mass index.
a
Parameter estimates from linear regression were adjusted for age, sex, smoking status, educational attainment, ethnic background, and BMI (except for analyses stratified by BMI).