Table 1.
Effect of Decoquinate on Liver and Blood Stages of Plasmodium Infection, as Represented by Its Half-Maximal Inhibitory Concentration (IC50)
Blood Stages (IC50) |
|||
Compound | Liver Stages (IC50) | Asexual | Sexual |
Decoquinate | 2.6 ± 0.7 | 10 ± 8 | 36 ± 30 |
Primaquine | 7500 | 11 000 ± 5000 [6] | No effect [6] |
Artemisinin | NA | 62 ± 14 | 92 ± 31 |
Atovaquone | NA | 1.8 ± 0.2 [6] | Slight reduction [6] |
IC50 data are mean nM ± SD. Published IC50 data given for comparison were taken from [6].
Abbreviation: NA, not available.