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Sensitivity of Ubiquinol:Cytochrome bc1 Activity to Decoquinate and Atovaquone on Isolated Mitochondria
| IC50 (mean μM ± SD) |
||
| Ubiquinol Cytochrome c Reductase | Decoquinate | Atovaquone |
| P. falciparum | 0.002 ± 0.0005 | 0.0002 ± 0.00003 |
| HEK293 | >10 | 0.327 ± 0.03 |
Abbreviation: P. falciparum, Plasmodium falciparum.
