Skip to main content
. 2012 Feb 28;12:77. doi: 10.1186/1471-2407-12-77

Table 2.

Course of Fatigue, Anxiety and Depression as assessed in 21 ovarian cancer patients with three different assessment instruments

BLa CT2b CT3 CT4 CT5 CT6 AC1b AC2 Constant Term/
Beta Coefficient
Reference
Valuesc
Hospital Anxiety and Depression Scale (HADS)c

Anxiety 7.0 (4.2) 6.1 4.5 4.5 3.9 4.1 4.5 4.1 (4.3) 5.7/-0.3 t = -2.80; p = 0.006 5.0
(3.4)

Depression 6.5 (3.8) 5.4 3 4.5 3.5 3.3 3.1 2.3 (3.6) 5.2/-0.3 t = -4.07; p < 0.001 4.7
(3.9)

Hamilton Anxiety and Depression Scale (HAMA/D)

Anxiety 15.0 (8.0) 11.0 11.4 10.4 8.3 7.5 9.2 7.6 (5.9) 12.8/-0.6 t = -3.01; p = 0.004 n.a.

Depression 11.7 (6.8) 8.1 7.9 7.6 5.6 6.6 5.2 4.7 (3.2) 9.3/-0.6 t = -3.58; p = 0.001 n.a.

Multidimensional Fatigue Inventory (MFI)c

General
Fatigue
13.2 (4.7) 13.4 11.9 12.8 11.8 11.7 9.7 7.8 (3.9) 13.4/-0.5 t = -4.62; p < 0.001 10.8
(3.7)

Physical
Fatigue
13.1 (3.9) 13.5 13.4 12.9 11.2 11.2 9.6 7.4 (4.4) 13.7/-0.5 t = -5.29; p < 0.001 11.1
(4.2)

Reduced
Activity
15.4 (4.8) 15.1 12.2 12.4 10.9 11.2 8.7 6.5 (3.6) 15.2/-1.0 t = -8.19; p < 0.001 10.5
(4.0)

Reduced
Motivation
7.5 (3.5) 7.4 6.5 7.9 6.4 6.3 6.2 5.6 (1.9) 7.5/-0.2 t = -2.98; p = 0.004 9.9
(3.5)

Mental
Fatigue
9.8 (5.1) 8.6 8.8 9.6 8.2 7.7 7.5 7.3 (4.3) 9.3/-0.2 t = -2.03; p = 0.046 9.2
(3.4)

a BL baseline (CT1)

b CT chemotherapy cycle, AC aftercare

c Reference values: HADS (female general population) [31]MFI-20 (general population > 60 y) [30]