Table 1.
Cell types | The percent (%) of cells | ANOVA | |||||||
---|---|---|---|---|---|---|---|---|---|
Control | 1 dpi | 2 dpi | 3 dpi | 4 dpi | 5 dpi | 6 dpi | 7 dpi | p | |
Lymphoblasts | 0 | 0 | 0.5 ± 0.1 | 3.2 ± 0.9** | 3.6 ± 0.9** | 18.9 ± 4.8** | 10.3 ± 2.7** | 2.8 ± 0.7** | < 0.001 |
Small lymphocytes | 34.2 ± 7.6 | 18.6 ± 4.3* | 25.7 ± 7.0 | 12.6 ± 3.5* | 11.2 ± 2.9* | 8.5 ± 2.6* | 8.0 ± 2.0* | 3.3 ± 1.0* | < 0.001 |
Medium lymphocytes | 13.2 ± 3.5 | 10.4 ± 2.2* | 10.6 ± 2.3* | 3.8 ± 0.8* | 7.1 ± 1.8 | 7.2 ± 2.1 | 8.4 ± 2.2 | 3.7 ± 0.8* | < 0.001 |
Large lymphocytes | 8.5 ± 3.1 | 11.0 ± 2.1 | 6.4 ± 1.2 | 6.3 ± 1.9 | 5.3 ± 1.1 | 5.4 ± 1.2* | 6.5 ± 1.9 | 6.5 ± 1.2 | < 0.001 |
Reactive lymphocytes | 0 | 6.1 ± 2.0** | 3.7 ± 0.8** | 3.8 ± 0.9** | 8.0 ± 2.0** | 4.5 ± 1.1** | 4.7 ± 1.1** | 14.8 ± 2.9** | < 0.001 |
Atypical lymphocytes | 0 | 4.3 ± 1.1** | 8.0 ± 1.8** | 7.0 ± 1.9** | 4.4 ± 1.0** | 5.4 ± 1.2** | 10.3 ± 2.8** | 14.8 ± 3.3** | < 0.001 |
Monoblasts | 0.5 ± 0.1 | 3.0 ± 0.4** | 3.7 ± 0.6** | 3.8 ± 1.1** | 7.1 ± 2.1** | 2.7 ± 0.8 | 2.8 ± 0.5* | 0.2 ± 0.1 | < 0.001 |
Monocytes | 7.7 ± 2.8 | 7.3 ± 2.1 | 8.5 ± 1.3 | 10.8 ± 2.2 | 9.7 ± 2.9 | 9.0 ± 2.3 | 7.5 ± 1.6 | 7.4 ± 1.4 | < 0.001 |
Metamyelocytes | 0 | 1.2 ± 0.3** | 3.7 ± 0.9** | 3.8 ± 1.0** | 6.2 ± 1.4** | 6.3 ± 1.5** | 7.5 ± 1.9** | 7.3 ± 2.0** | < 0.001 |
Band neutrophils | 7.7 ± 3.0 | 12.8 ± 3.4** | 14.9 ± 2.5** | 20.3 ± 3.4** | 12.4 ± 3.0 | 4.5 ± 1.1* | 5.6 ± 1.2 | 5.6 ± 1.8 | < 0.001 |
Segmented neutrophils | 23.1 ± 5.5 | 19.5 ± 4.0* | 5.3 ± 0.9* | 8.9 ± 1.5* | 3.5 ± 0.9* | 3.6 ± 0.9* | 3.7 ± 0.8* | 1.9 ± 0.3* | < 0.001 |
Eosinophils | 4.9 ± 1.1 | 4.9 ± 1.3 | 1.6 ± 0.2* | 3.8 ± 0.8 | 1.8 ± 0.5* | 3.6 ± 0.7 | 2.8 ± 0.6 | 1.9 ± 0.2* | < 0.001 |
Basophils | 0.2 ± 0.01 | 0.3 ± 0.02 | 0.4 ± 0.02 | 0.1 ± 0.02 | 0.3 ± 0.1 | 0.5 ± 0.1 | 0.4 ± 0.1 | 0.4 ± 0.1 | < 0.001 |
Plasmocytes | 0 | 0 | 1.6 ± 0.3** | 3.2 ± 0.5** | 2.7 ± 0.7** | 3.6 ± 0.9** | 4.7 ± 0.9** | 4.6 ± 1.1** | < 0.001 |
Dead cells | 0 | 0.6 ± 0.1 | 5.3 ± 1.0** | 8.9 ± 1.6** | 16.8 ± 3.4** | 16.2 ± 4.0** | 16.8 ± 3.8** | 24.8 ± 4.8** | < 0.001 |
Control represents the mean of given cell type for each time point of infection
* Significant decrease compared with control (p < 0.05-p < 0.001)
** Significant increase compared with control (p < 0.05-p < 0.001)