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. 2012 Mar 20;9(3):e1001194. doi: 10.1371/journal.pmed.1001194

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Collaboration of Observational HIV Epidemiological Research in Europe (COHERE).

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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These plots apply to hypothetical patients whose CD4 cell count remains within the same CD4 stratum while on cART with a suppressed viral load. Plot (A) shows a Kaplan Meier plot of the probability of AIDS event-free survival over time. Plot (B) shows a plot of log(−log [probability of AIDS event-free survival]) against log(time). The roughly parallel lines of plot (B) suggest that a proportional hazards model is appropriate for these data. Both plots use a method appropriate for a time-dependent CD4 cell count (see [16]).