Table 1. Protective efficacy of MAbs in mice.
| MAb | Treatment timea | Mean time to deathb | No of survivors/total | Survival (%) |
| 1H3 | −1 | 6.60±0.61 (n = 10) | 0/15 | 0 |
| +1 | 8.10±0.74 ( n = 9) | 6/15 | 40 | |
| 2G4 | −1 | 7.86±0.74 ( n = 14) | 1/15 | 7 |
| +1 | 8.00 ( n = 6) | 9/15 | 60 | |
| 4G7 | −1 | 7.08±0.74 ( n = 14) | 1/15 | 7 |
| +1 | 8.25±0.43 ( n = 4) | 11/15 | 73 | |
| 5D2 | −1 | 8.00±1.00 ( n = 2) | 13/15 | 87 |
| +1 | N/Ac | 15/15 | 100 | |
| 5E6 | −1 | 8.25±0.43 ( n = 4) | 11/15 | 73 |
| +1 | 7.00 ( n = 1) | 14/15 | 93 | |
| 7C9 | −1 | 7.75±0.43 ( n = 4) | 11/15 | 73 |
| +1 | 8.00±0.82 ( n = 3) | 12/15 | 80 | |
| 7G4 | −1 | 8.07±0.59 ( n = 14) | 1/15 | 7 |
| +1 | N/Ac | 15/15 | 100 | |
| 10C8 | −1 | 7.64±1.17 ( n = 14) | 1/15 | 7 |
| +1 | 8.50±0.50 ( n = 2) | 13/15 | 87 | |
| PBS | −1 | 6.60±0.80 ( n = 5) | 0/5 | 0 |
| +1 | 5.00±0.60 ( n = 10) | 0/10 | 0 |
a
Mice were treated i.p. with 100 µg of MAb at the indicated days before or after challenge with 1000 LD50 of the mouse-adapted Ebola virus.
b
Data for animals that died (number of animals in calculation).
c
N/A: not applicable.