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. 2012 Mar 20;6(3):e1567. doi: 10.1371/journal.pntd.0001567

Table 4. Histopathological scores from left/right hemisphere of the brain and spinal cord.

Group Animal # Day PI FC BG TH OC CB/BS SC
Vehicle Control 53-09 21 0/0 0/0 0/0 0/0 0/0 0
60-09 21 0/0 0/0 0/0 0/0 0/0 0
68-01 21 0/0 0/0 0/0 0/0 0/0 0
359-09 21 0/0 0/0 0/0 0/0 0/0 0
rVSV-wt 56-09* 6 4/4 4/4 3/2 1/1 2/2 3
67-01** 5 2/3 2/1 0/0 0/0 0/1 1
362-09 21 4/1 1/1 1/1 0/0 0/2 3
rVSV-ZEBOV-GP 352-09 21 1/1 1/0 1/0 0/0 0/0 0
354-09 21 1/1 0/0 1/0 0/0 0/0 0
357-09 21 1/0 0/0 0/0 0/0 1/0 0
358-09 21 0/0 1/0 1/0 0/1 0/0 0
360-09 21 1/0 0/0 0/0 0/0 0/0 0
361-09 21 1/0 0/0 0/0 0/0 0/0 0
363-09 21 0/0 0/0 0/0 0/0 0/0 0
rVSV-MARV-GP 52-09 21 0/1 1/0 1/0 0/0 0/0 0
57-09 21 0/0 0/0 0/0 0/0 0/0 0
59-09 21 1/0 0/0 1/0 0/0 0/0 0
61-09 21 0/0 0/0 0/0 0/0 0/0 0
355-09 21 1/0 1/4 0/0 0/0 0/0 0
356-09 21 1/1 0/0 0/0 0/0 0/0 0
364-09 21 1/0 0/0 0/1 0/0 0/1 0

Left score #/Right score #; Scores; 0 = no lesions, 1 = minimal perivascular inflammatory infiltrate, no gliosis, no neurodegeneration, no satellitosis, and no necrosis, 2 = mild perivascular inflammatory infiltrate, mild gliosis, no neurodegeneration, no satellitosis, and no necrosis, 3 = moderate inflammatory infiltrate with moderate gliosis, mild neurodegeneration, mild satellitosis, and mild necrosis, and 4 = severe inflammatory infiltrate with moderate to severe gliosis, neurodegeneration, satellitosis, and necrosis.

FC = frontal cortex, BG = basal ganglia, TH = thalamus, OC = occipital cortex, CB/BS = cerebellum/brain stem, SC = spinal cord; PI = post-inoculation.