Table 2. Site-specific hypothalamic 5-HT2C mRNA editing in ob/ob mice compared to control.
Edit site percentage (%) | A | B | E | C | D |
Lean Control (n = 8) | 87.58 | 75.23 | 3.67 | 24.39 | 55.18 |
ob/ob (n = 8) | 90.01 | 76.67 | 3.01 | 23.7 | 50.65 |
Δ (%) | ↑2.43 | ↑1.44 | ↓0.66 | ↓0.69 | ↓4.5 |
P-value | 2.07*10−8 | - | - | - | 4.47*10−11 |