Table 6. Baseline Levels of hsCRP, IL-6 and D-dimer for HIV Uninfected Participants, and Participants with Early and Advanced HIV Infection.
HIV uninfected (n = 80) | Early HIV infection* (n = 80) | Advanced HIV infection** (n = 100) | |
Median Baseline Characteristics | |||
Age | 37 | 38 | 36 |
(25th, 75th %ile) | (33, 42) | (35, 40) | (33, 39) |
Sex (% female) | 31 | 31 | 35 |
CD4 + count (cells/mm3) | NA | 546 | 110 |
(25th, 75th %ile) | NA | (409, 709) | (58, 175) |
HIV RNA | NA | 4,025 | 148,000 |
(25th, 75th %ile) | NA | (1,036, 27,250) | (64,900, 304,000) |
Biomarker Levels (median; 25th, 75th %ile) |
NA = not applicable.
CD4+ T cell count >350 cells/ml.
CD4+ T cell count ≤200 cells/mL (or <14% for patients post-splenectomy) and/or any history of or current AIDS defining illness and with hemoglobin >9 g/dL (>8 g/dL for women), neutrophil count >500 cells/mL, platelet count >250/uL, and serum liver transaminases below five times the upper limit of normal.
Comparisons between the different groups are adjusted for age, sex and BMI.