Table 3. Age-adjusted incidence rates and rate ratios of potentially HPV-associated and non HPV-associated HNC by sex and race/ethnicity^a, 1995–2005.

		Age-adjusted incidence rates (95% CI)			Rate ratios (95% CI)
Category	Sub-Category	NH White	NH Black	Hispanic	NH Black/NH White	Hispanic/NH White
All HNC Sites	Total	11.71 (11.66–11.76)	14.67 (14.50–14.84)	8.34 (8.21–8.48)	1.25* (1.24–1.27)	0.71* (0.70–0.72)
	Males	18.56 (18.47–18.65)	26.45 (26.10–26.80)	14.61 (14.33–14.89)	1.43* (1.41–1.45)	0.79* (0.77–0.80)
	Females	5.84 (5.79–5.89)	5.96 (5.82–6.10)	3.34 (3.22–3.46)	1.02 (1.00–1.05)	0.57* (0.55–0.59)
HPV-Associated Sites	Total	3.04 (3.02–3.07)	3.45 (3.37–3.53)	1.83 (1.77–1.89)	1.13* (1.10–1.16)	0.60* (0.58–0.62)
	Males	5.00 (4.95–5.05)	6.12 (5.96–6.29)	3.25 (3.13–3.38)	1.22* (1.19–1.26)	0.65* (0.63–0.68)
	Females	1.27 (1.25–1.29)	1.39 (1.33–1.46)	0.64 (0.59–0.69)	1.10* (1.04–1.15)	0.51* (0.47–0.55)
Non HPV-Associated Sites	Total	8.67 (8.62–8.71)	11.22 (11.08–11.37)	6.51 (6.39–6.64)	1.30* (1.28–1.31)	0.75* (0.74–0.77)
	Males	13.56 (13.48–13.63)	20.33 (20.02–20.64)	11.36 (11.11–11.61)	1.50* (1.48–1.52)	0.84* (0.82–0.86)
	Females	4.57 (4.53–4.61)	4.57 (4.44–4.69)	2.69 (2.59–2.80)	1.00 (0.97–1.03)	0.59* (0.57–0.61)

HNC: head and neck cancer; HPV: human papillomavirus; 95% CI: 95% Confidence Interval; NH: Non-Hispanic.

Rates are per 100,000 and age-adjusted to the 2000 U.S. Standard Population (19 age groups – Census P25-1130).

Confidence intervals (Tiwari model) are 95% for rates and ratios.

^*The rate is significantly different than the rate for Non-Hispanic Whites (p<0.05).

^aAny cases with an ‘Unknown’ or ‘Other’ race were not included in the analysis.