Table 2. Effect of atorvastatin treatment on levels of cholesterol and immune mediators.
Parameter | Placebo (median) [IQR] | Atorvastatin (median) [IQR] | |||
Total cholesterol (mmol/l) | At baseline | 4.02 [1.03] | n.s. | 3.93 [0.96] | p<0.0001 |
At 3 months | 3.89 [1.13] | 2.56 [0.78] | |||
CRP (mg/l) | At baseline | 0.84 [2.24] | n.s. | 0.86 [2.17] | pā=ā0.029 |
At 3 months | 0.64 [1.41] | 0.69 [1.07] | |||
IL-6 (pg/ml) | At baseline | 0.58 [0.54] | n.s. | 0.75 [1.08] | n.s. |
At 3 months | 0.67 [0.50] | 0.56 [1.62] | |||
Cholesterol above baseline median | At baseline | 4.53 [0.70] | n.s. | 4.33 [0.57] | p<0.0001 |
At 3 months | 4.44 [0.96] | 2.94 [0.61] | |||
Cholesterol below baseline median | At baseline | 3.57 [0.39] | n.s. | 3.39 [0.69] | p<0.0001 |
At 3 months | 3.47 [0.63] | 2.35 [0.76] | |||
CRP above baseline median | At baseline | 2.55 [2.75] | n.s. | 2.37 [1.90] | pā=ā0.037 |
At 3 months | 1.73 [3.39] | 1.24 [0.86] | |||
CRP below baseline median | At baseline | 0.33 [0.23] | n.s. | 0.24 [0.40] | n.s. |
At 3 months | 0.36 [0.31] | 0.21 [0.34] |