Table 5. One-Way Sensitivity Analyses of Switching Points: Outcomes.
| ICER (ΔC/ΔE, $), 4 mo | ICER (ΔC/ΔE, $), 12 mo | |||
| Parameter Varieda | B-A | C-B | B-A | C-B |
| Cocaine Use | ||||
| Occasionsb Used, past 30 days | +5% ($123) | −30% | −5% | −115% |
| Episodes per Day, past 30 days | −15% | −15% | +5% ($2,491) | −50% |
| Cocaine Free Days, past 30 days | +5% ($135) | +5% ($1,678) | +5% ($197) | −10% |
| Abstaining, past 30 days | −5% | −10% | +5% ($8,755) | +10% ($78,525) |
| Abstaining, past 4 months | −10% | −15% | −15% | +15% ($62,820) |
| Alcohol Consumption | ||||
| Total Drinks, past 7 days | +10% ($347) | −35% | −40% | −15% |
| Drinks per Day, past 7 days | +25% ($672) | −50% | −30% | −25% |
| Preventing Heavy Drinkers,c past 7 days | +5% ($48,150) | −5% | −5% | −5% |
| Abstaining, past 30 days | −10% | +15% ($628,200) | −10% | +10% ($49,595) |
Abbreviations: ICER, incremental cost effectiveness ratio, which is the difference in cost divided by the difference in effectiveness as compared with the next least costly intervention and indicates cost per additional outcome achieved; A, SI intervention; B, WWE intervention; C, 4ES intervention.
Table S2 includes complete results of ICERs at 5% increments en route to the switching points.
Percentage varied indicates percentage change of base case value for more costly alternative only, whereas base case of its comparator remain the same. A negative percentage change indicates less effective intervention than the base case, which may or may not indicate a mean lower than the base case (see Table 2). A positive percentage change indicates a more effective intervention than base case. Included in parentheses is the corresponding ICER.
Occasions = days used * times per day.
“Heavy drinker” includes participants who drink ≥4 drinks per day of the days participants drank alcohol.