Figure 3. Inhibition of HIV-1 infection by CB₂ activation is enhanced in CD4+ T cells infected prior to activation.

(A–C) Infection, as measured by GFP expression, in primary CD4+ T cells activated with mitogen (A) for 4 days prior or (B) 4 days after treatment with pertussis toxin or 100 nM of the CB2 agonist JWH-133 (A, B) in a representative donor and (C) in multiple donors (mean±SEM; n = 4 donors; *p<0.05).