Figure 6. Graphical representation of functional interactions and regulatory interactions of up and downregulated genes.

DosR acts as a master regulator, regulating the expression of a number of upregulated genes. A probable oxidoreductase Rv0082 under the regulation of DosR associates with the subunits of aerobic respiratory machine NADH oxidoreductase complex. Upregulated proteins are colored in green, downregulated proteins are colored in red and transcription factors are colored in blue. Directed edge denotes gene regulation and undirected edge is a protein functional linkage.