Table 2.
18-month postnatal transmission of HIV among children uninfected at 4 weeks of age and according to different thresholds of maternal antenatal CD4 count. Pooled analysis of the Vertical Transmission Study (South Africa, 2001–2007) and the Ditrame Plus Study (Côte d’Ivoire, 2001–2005). N=1151.
Antenatal maternal CD4 count (cells/ml) | N | Number of children HIV-infected through breastfeeding | HIV postnatal transmission (%) | 95% confidence interval |
---|---|---|---|---|
< 200 | 119 | 15 | 15.3 | 9.5–24.2 |
≥ 200 | 1032 | 57 | 6.2 | 4.9–8.0 |
< 250 | 181 | 20 | 11.0 | 5.3–16.2 |
≥ 250 | 970 | 52 | 5.4 | 3.5–6.5 |
< 350 | 353 | 38 | 12.6 | 9.3–16.9 |
≥ 350 | 798 | 34 | 4.8 | 3.4–6.6 |
< 200 | 119 | 15 | 15.3 | 9.5–24.2 |
200–349 | 234 | 23 | 11.3 | 7.6–16.5 |
350–500 | 320 | 18 | 6.3 | 4.9–9.1 |
≥ 500 | 478 | 16 | 3.7 | 2.3–6.0 |
Adapted from Becquet et al. CROI 2008 [35]