Figure 8. There is increased mineralization induced by BMP2 in the B6.C3H-1-12 mice.
BMSCs isolated from the C57BL/6J and B6.C3H-1-12 female mice were cultured in 24 well plates for 10 days. Cells were treated with BMP2 (40nM) or left non-stimulated to serve as controls. After 12 days cells were stained for mineralization with von Kossa. BMP2 stimulation significantly increased mineralization by BMSCs isolated from the C57BL/6J and B6.C3H-1-12. BMP2 treatments were normalized to corresponding control. * Indicates significance as detected by student t test (p<0.05).