Table 1.
Absolute values in baseline condition | Absolute values in stimulation (Functional percentage changes) | |||
---|---|---|---|---|
| ||||
Anesthetic | isoflurane | α-chloralose | isoflurane | α-chloralose |
CBF (ml/g/min)b | 1.05±0.25 | 0.66±0.14* | 1.21±0.28† (15±3%) | 1.06±0.23† (60±7%) |
TTa (ms) | 381±86 | 396±48 | 376± 86 (−1±3%) | 383±44 (−3±3%) |
TTc (ms) | 636±83 | 714±37 | 627± 92 (−2±3%) | 698±40 (−2±2%) |
CBVa (ml/100g) | 0.59±0.26 | 0.30±0.14* | 0.69±0.29† (19±9%) | 0.44±0.19† (46±17%) |
All values were obtained from contralateral somatosensory cortical ROIs with 3×3 pixels (mean ± SD). TTa: arterial blood transit time from the carotid arteries to cortical arteries; TTc: arterial blood transit time from carotid arteries to capillaries; CBVa: cerebral arterial blood volume.
CBF was measured with diffusion gradients (b = 50 s/mm2).
Significantly different from values in the baseline condition under isoflurane anesthesia (p < 0.05, independent two sample t-test).
Significantly different from values in the baseline condition under the same anesthesia (p < 0.05, paired two-tailed t-test).