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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Arch Toxicol. 2011 Nov 22;86(4):633–642. doi: 10.1007/s00204-011-0778-y

Fig. 1. NRF-1 transcription is regulated by ER in HUVEC.

Fig. 1

(A) HUVEC cells were treated with EtOH, 10 nM E2, 100 nM 4-OHT, 100 nM RAL, 10 nM DPN, or 10 nM PPT for 4 h; where indicated, cells were pretreated with 100 nM ICI 182,780 (ICI). (B) HUVEC cells were pre-treated with Wortmannin or PD98059 for 1 h +/− 100 nM 4-OHT and 100 nM RAL. *, p < 0.05 versus EtOH control; ** p < 0.05 versus same treatment without ICI.