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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2012 Apr 1;82(5):1559–1566. doi: 10.1016/j.ijrobp.2010.12.032

Fig. 4.

Fig. 4

Effect of a single dose of whole brain irradiation on collagen type IV expression in rat brain. Immunoreactivity of collagen type IV was visualized in rat brain (A–D). A single dose of whole brain irradiation markedly and significantly reduced the protein expression levels of collagen type IV in rat brains 24 h after irradiation (E). Images (A–D) are as viewed under microscope at 100×. Data shown are mean ± SEM for each group (n=4). *Statistically significant from control (p<0.05). A: sham-irradiation (Control); B: 4 h post-irradiation; C: 8 h post-irradiation; D: 24 h post-irradiation; E: quantitative analysis of fluorescence intensity.