Table 1.
Sequences of LAH4 or LAH6 derivatives used in this study. Histidine residues are marked in bold
| Peptide | Sequence | Peptide length (residues) |
Average Hydro- phobicity(H)* |
|---|---|---|---|
| LAH4-L1 | KKALLAHALHLLALLALHLAHALKKA | 26 | 0.050 |
| LAH6-X1L | KHKLLHLLHLLALLALHLLHLLKHK | 25 | 0.024 |
| LAH6-X1L-W | KHKLLHLLHLLALLWLHLLHLLKHK | 25 | 0.028 |
As determined by the Eisenberg (1982) Consensus scale (Ile, 0.73; Phe, 0.61; Val, 0.54; Leu, 0.53;Trp, 0.37; Met, 0.26; Ala, 0.25; Gly, 0.16; Cys, 0.04; Tyr, 0.02; Pro, −0.07; Thr, −0.18; Ser, −0.26; His,−0.40; Glu, −0.62; Asn, −0.64; Gln, −0.69; Asp, −0.72; Lys, −1.1; and Arg, −1.8).