Table I.

Isolated metastasis to the bones of the extremities as the first manifestation of endometrial cancer – review of the literature

Author/year (references)	Age [years]	Histology	Grade	Bone involved	Other metastasis	Treatment	Survival [months]
Vanecko RM, et al./1967 [10]	54	–	–	Fibula	–	–	–
Onuba O/1983 [13]	57	Endometrioid adenocarcinoma	–	Tibia	Lung, kidney	–	–
Cooper JK, et al./1994 [7]	59	Endometrioid adenocarcinoma	2	Calcaneus	No	Chemotherapy, radiotherapy	> 60
Petru E, et al./1995 [11]	61	Endometrioid adenocarcinoma	1	Tarsus	No	Chemotherapy, hormone therapy	10
Malicky ES, et al./1997 [12]	44	Endometrioid adenocarcinoma	2	Femur	No	Radiotherapy, hormone therapy	> 12
Manolitsas TP, et al./2002 [3]	76	Endometrioid adenocarcinoma	3	Calcaneus	No	Radiotherapy	20
Uharcek P, et al./2006 [8]	67	Endometrioid adenocarcinoma	1	Calcaneus, talus and metatarsal bones	No	Surgery, chemotherapy, hormone therapy	> 20
Loizzi V, et al. 2006 [5]	73	Endometrioid adenocarcinoma	3	Tibia	No	Chemotherapy	9
Kaya A, et al./2007 [9]	70	Endometrioid adenoca rcinoma	1	Tibia	No	Radiotherapy	> 47
This case, 2010	74	Endometrioid adenocarcinoma	2	Calcaneus, talus and metatarsal bones	No	Radiotherapy	> 40