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. 2011 Aug 16;1(8):e31. doi: 10.1038/tp.2011.27

Table 2. Probabilities and Pearson correlation between brain protein and mRNA levels and subject age, postmortem intervals and pH.

  Age
PMI
pH
     
  P-value R2 P-value R2 P-value R2
Protein            
cPLA2 0.589 0.02 0.617 0.0142 0.151 0.111
sPLA2 0.152 0.11 0.856 0.0019 0.238 0.076
iPLA2 0.812 0.00 0.779 0.0045 0.180 0.097
COX-1 0.417 0.04 0.673 0.0101 0.163 0.105
COX-2 0.498 0.03 0.409 0.0381 0.728 0.007
mPGES 0.892 0.00 0.253 0.0718 0.367 0.045
cPGES 0.768 0.00 0.938 0.0003 0.125 0.126
12-LOX 0.089 0.00 0.914 0.0010 0.613 0.022
15-LOX 0.640 0.01 0.443 0.0350 0.139 0.124
p450 Epoxy 0.091 0.15 0.997 0.0000 0.235 0.077
TNF-α 0.432 0.03 0.341 0.0505 0.243 0.096
IL-1β 0.988 0.00 0.881 0.0013 0.898 0.001
Cd11b 0.998 0.00 0.828 0.0027 0.879 0.001
GFAP 0.357 0.05 0.277 0.0733 0.979 0.000
SYP 0.572 0.02 0.345 0.0497 0.845 0.002
Drebrin 0.323 0.05 0.545 0.0208 0.203 0.089
             
mRNA            
cPLA2 0.800 0.00 0.120 0.120 0.520 0.027
sPLA2 0.120 0.12 0.790 0.000 0.410 0.030
iPLA2 0.270 0.06 0.180 0.090 0.100 0.130
COX-1 0.960 0.00 0.460 0.020 0.610 0.010
COX-2 0.330 0.05 0.300 0.050 0.070 0.160
mPGES 0.900 0.00 0.380 0.042 0.700 0.000
cPGES 0.350 0.04 0.880 0.000 0.190 0.090
12-LOX 0.350 0.04 0.200 0.080 0.190 0.090
15-LOX 0.490 0.02 0.420 0.030 0.690 0.000
p450 Epoxy 0.430 0.03 0.410 0.030 0.960 0.000
TNF-α 0.780 0.00 0.340 0.050 0.150 0.110
IL-1β 0.310 0.09 0.950 0.000 0.580 0.020
Cd11b 0.620 0.01 0.790 0.000 0.860 0.004
GFAP 0.350 0.05 0.270 0.070 0.970 0.000
SYP 0.810 0.00 0.730 0.000 0.650 0.010
Drebrin 0.170 0.16 0.630 0.020 0.750 0.000

Abbreviations: COX, cyclooxygenase; cPGES, cytosolic prostaglandin synthase; cPLA2, cytosolic phospholipase A2, GFAP, glial fibrillary acidic protein; iPLA, calcium-independent phospholipase A2, LOX, lipoxygenase; mPGES, membrane prostaglandin synthase; p450 epoxy, cytochrome p450 epoxygenase; sPLA2, secretory phospholipase A2; TNF-α, tumor necrosis factor-alpha; SYP, synaptophysin.