Table 1. Bivariate relationships among midbrain 5-HTT availability, 5-HTTLPR, left and right amygdala volume, left and right amygdala activation, smoking status, sex and age.
| (1) 5-HTTLPR | (2) | (3) | (4) | (5) | (6) | (7) | (8) | |
|---|---|---|---|---|---|---|---|---|
| (2) 5-HTT mid | −0.018 (P=0.448)* | |||||||
| (3) L Amy Vol | −0.297 (P=0.015)* | −0.039 (P=0.782) | ||||||
| (4) R Amy Vol | −0.28 (P=0.020)* | 0.053 (P=0.702) | 0.268 (P=0.025)* | |||||
| (5) L Amy BOLD | 0.289 (P=0.017)* | −0.001 (P=0.496)* | −0.094(P=0.249)* | −0.351 (P=0.005)* | ||||
| (6) R Amy BOLD | 0.157 (P=0.129)* | −0.246 (P=0.037)* | −0.043 (P=0.379)* | −0.199 (P=0.075)* | 0.70 (P<0.001)* | |||
| (7) Smoking status | 0.033 (P=0.812) | −0.125 (P=0.184)* | −0.029 (P=0.834) | 0.050 (P=0.722) | 0.136 (P=0.327) | 0.168 (P=0.225) | ||
| (8) Sex | 0.196 (P=0.156) | −0.107 (P=0.220)* | −0.186 (P=0.089)* | −0.113 (P=0.209)* | 0.089 (P=0.556) | 0.205 (P=0.137) | −0.117 (P=0.339) | |
| (9) Age | −0.170 (P=0.220) | −0.152 (P=0.137)* | −0.164 (P=0.237) | 0.101 (P=0.468) | −0.165 (P=0.117)* | −0.123 (P=0.187)* | 0.175 (P=0.399) | −0.082 (P=556) |
Abbreviations: 5-HTT, serotonin transporter protein; 5-HTTLPR, serotonin transporter-linked promoter region; 5-HTT Mid, 5-HTT availability in the midbrain; L Amy BOLD, left amygdala activation; L Amy Vol, left amygdala volume; R Amy BOLD, right amygdala activation; R Amy Vol, right amygdala volume.
Pearson's correlation coefficients and corresponding P-values. 5-HTTLPR (0=LL, 1=S); smoking status (0=non-smoker, 1=smoker), sex (0=male, 1=female), N=54. Bold indicates significance at P<0.05; *-one-tailed.