Figure 2.

Differences between ‘unaffected' siblings and controls with no family history of autism in the neural response to happy versus neutral faces. Activation differences (means±s.e.m.) between the functional magnetic resonance imaging response to happy and neutral faces in adolescents with autism (n=40), unaffected siblings (n=40) and controls (n=40). Activation map corrected for multiple comparisons at P<0.05 family-wise error corrected, and overlaid onto a three-dimensional-rendered template brain within MRIcron. STS, superior temporal sulcus.