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. 2012 Feb 28;2(2):e85. doi: 10.1038/tp.2012.7

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Copyright © 2012 Macmillan Publishers Limited

This work is licensed under the Creative Commons Attribution-NonCommercial-No Derivative Works 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

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(a): Scatterplot of the mean blood-oxygen level dependent (BOLD) working memory (WM)–control values plotted against age for all three factors. Black lines connect repeated measures for individuals who participated in both round 1 and 2. Red lines represent the mean predicted BOLD signal as a function of age, as obtained from the mixed-model analysis using the inverse of age as a fixed effect. (b) Scatterplot of the mean BOLD WM–control values of Factor 1 against Visuospatial WM (VSWM) capacity. Black lines connect repeated measures. The red line represents the mean-predicted BOLD signal for each age group, as obtained from the mixed-model analysis using the inverse of age as a factor.