Table 2. Factors associated with resistance to tuberculosis drugs, Zhejiang Province, China, 1999–2008*.
| Characteristic | Coefficient | OR (95% CI) | p value |
|---|---|---|---|
| Model 1: Risk factors associated with resistance to isoniazid | |||
| Constant | −4.10 | 0.02 | |
| Year | 0.23 | 1.26 (0.87–1.84) | 0.221 |
| Rifampin | 2.99 | 19.91 (12.91–30.70) | <0.001 |
| Age 0–14 years | 0.89 | 2.43 (0.20–34.90) | 0.51 |
| Age 15–64 years | −0.49 | 0.61 (0.40–0.94) | <0.05 |
| Sex | 0.16 | 1.17 (0.80–1.71) | 0.43 |
| Re-treatment | 0.62 | 1.85 (1.24–2.76) | <0.005 |
| Model 2: Risk factors associated with resistance to rifampin | |||
| Constant | −3.33 | 0.10 | <0.001 |
| Year | −0.53 | 0.59 (0.38–0.93) | <0.05 |
| Isoniazid | 2.99 | 19.85 (12.92–30.51) | <0.001 |
| Age 0–14 year | −1.74 | 0.18 (0.02–1.29) | 0.09 |
| Age 15–64 year | −0.05 | 1.02 (0.62–1.66) | 0.95 |
| Sex | −0.30 | 0.73 (0.47–1.16) | 0.19 |
| Re-treatment | 1.84 | 6.29 (4.15–9.53) | <0.001 |
| Model 3: Risk factors associated with MDR TB | |||
| Constant | −2.78 | 0.62 | <0.001 |
| Year | −0.16 | 0.86 (0.61–1.21) | 0.384 |
| Age 0–14 year | −0.69 | 0.52 (0.06–4.36) | 0.56 |
| Age 15–64 year | −0.45 | 0.62 (0.40–0.96) | <0.05 |
| Sex | −0.17 | 0.86 (0.58–1.23) | 0.37 |
| Re-treatment | 2.20 | 9.01 (6.39–12.68) | <0.001 |
*Reference groups are >65 years for age, female for sex, and new for re-treatment. OR, odds ratio; MDR TB, multidrug-resistant tuberculosis.