Table 2.
Growth-inhibitor activities of selected 37:63 CH:MM nylon-3 random copolymers toward four bacteria and lytic activity toward human red blood cells.
| Polymer | na | Fb | MIC (µg/mL)c | MHC (µg/mL)d |
|||
|---|---|---|---|---|---|---|---|
| E. coli | B. subtilis | S. aureus | E. faecium | ||||
| 1 | 32 | - | 200 | 6.25 | 200 | 50 | 800 |
| 2 | 25 | - | 12.5 | 3.13 | 25 | 12.5 | 800 |
| 1B-a | 26 | 0.86 | 200 | 6.25 | 400 | 100 | 1600 |
| 1B-b | 31 | 1.6 | 200 | 6.25 | 200 | 50 | 1600 |
| 1C-a | 29 | 0.53 | 50 | 6.25 | 100 | 25 | 25 |
| 1C-b | 32 | 0.88 | 50 | 12.5 | 200 | 50 | 3.13 |
| 2B-a | 19 | 1.1 | 25 | 3.13 | 50 | 25 | 800 |
| 2B-b | 25 | 1.9 | 25 | 6.25 | 100 | 25 | 800 |
a
The average number of the specific C-terminal functional groups per polymer chain.
b
MIC = minimum inhibitory concentration.
c
MHC = minimum hemolytic concentration.