Table 1.
Clinical symptoms of ferrets infected with A(H3N2)v influenza viruses
| Virus exposure | No. with weight loss (mean maximum weight loss, %) | No. with fever (mean maximum temperature increase, °C) | Lymphopenia at 3 dpi,* % | No. with virus detection (peak titer, log10 pfu/mL) | No. with seroconversion (HI geometric mean titer) |
| IN/11 | |||||
| Inoculated | 3/3 (10.8) | 3/3 (1.3) | 16.6 | 3/3 (7.1) | 3/3 (1280) |
| DC contact | 3/3 (2.8) | 3/3 (1.2) | ND | 3/3 (5.3) | 3/3 (1280) |
| RD contact | 3/3 (2.9) | 3/3 (1.2) | ND | 3/3 (5.2) | 3/3 (1280) |
| MN/10 | |||||
| Inoculated | 3/3 (8.3) | 3/3 (1.1) | 23.8 | 3/3 (5.9) | 3/3 (403) |
| DC contact | 3/3 (6.9) | 3/3 (0.9) | ND | 3/3 (5.5) | 3/3 (403) |
| RD contact | 3/3 (15.9) | 3/3 (1.3) | ND | 3/3 (5.5) | 3/3 (254) |
| PA/10 | |||||
| Inoculated | 3/3 (10.3) | 3/3 (1.5) | 19.0 | 3/3 (6.1) | 3/3 (806) |
| DC contact | 3/3 (11.5) | 3/3 (1.4) | ND | 3/3 (5.5) | 3/3 (640) |
| RD contact | 3/3 (10.8) | 3/3 (1.2) | ND | 3/3 (6.7) | 3/3 (640) |
| KS/09 | |||||
| Inoculated | 3/3 (9.1) | 3/3 (1.6) | 13.2 | 3/3 (5.2) | 3/3 (1015) |
| DC contact | 3/3 (1.5) | 3/3 (0.5) | ND | 3/3 (5.9) | 3/3 (806) |
| RD contact | 2/3 (16.5) | 2/3 (0.5) | ND | 2/3 (4.5) | 2/3 (453) |
ND, not determined.
*Mean percentage decrease in lymphocytes determined at 3 dpi compared with baseline measurements.