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. 2012 Feb 10;109(10):E605–E612. doi: 10.1073/pnas.1110666109

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Fig. 2. — Photoreceptor death requires dredd. Cross-sections (0.5 μm) of retinas of ydredd^B118w flies raised in darkness for 6 d (A), ydredd^B118w flies exposed to light for 6 d (B), dredd^B118wnorpA mutants raised in the dark for 6 d (C), ydredd^B118wnorpA flies exposed to 6 d of light (D), and ywnorpA flies exposed to 6 d of constant light (E) are shown. (Scale bar, 17.5 μm.) (F) Ratio of the total number of discernable rhabdomeres to the total number of ommatidia was used as a measure of photoreceptor viability in the indicated genotypes. Data from 6-d light-exposed yw flies are included as a reference in the yellow histogram bar to compare the effects of genetic background. Ratios for ydredd^B118w (dark), 6.73 ± 0.047 (110 ommatidia, 4 flies); for ydredd^B118w (light), 5.4 ± 0.34 (66 ommatidia, 3 flies); for ydredd^B118wnorpA (dark), 5.19 ± 0.65 (58 ommatidia, 3 flies); for ydredd^B118wnorpA (light), 6.68 ± 0.08 (114 ommatidia, 5 flies); and for ywnorpA (light), 1.09 ± 0.07 (92 ommatidia, 6 flies) are shown. Data are the mean ± SEM.