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. 2012 Feb 21;109(10):3927–3931. doi: 10.1073/pnas.1119858109

Fig. 5.

Fig. 5.

Absence of hematopoietic cell TFPI causes increased thrombus volume in F8−/− mice in a femoral vein electrolytic injury model. (A) Accumulation of platelets and (B) fibrin at the site of injury in mice in Tfpi+/−;F8−/− mice transplanted with Tfpi+/+ hematopoietic cells (□; n = 9) or with Tfpi−/− hematopoietic cells (X; n = 15). Data points were determined every 2 min, with error bars showing the SEM. The fibrin accumulation in mice lacking hematopoietic cell TFPI was significantly greater than in mice transplanted with Tfpi+/+ hematopoietic cells at 10–60 min (P < 0.05).