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. 2012 Feb 6;109(10):E613–E621. doi: 10.1073/pnas.1115029109

Fig. 4.

Fig. 4.

Repression of ISG expression by EMSY is BRCA2-dependent. (A) Expression of IFITM1, ISG15, and Viperin was measured by real-time RT-PCR in HMEC-tert cells transduced with the indicated constructs. (Left) Data are represented as fold change in the expression of these genes in cells transduced with the indicated constructs, and error bars show the SD (n = 3). (Right) Western blot analysis of the same samples is shown. shCon, sh control. (B) Data in A were reanalyzed to show the fold repression of IFITM1, ISG15, and Viperin in EMSY and EMSY + shBRCA2-transduced HMEC-tert cells. Error bars show the SD (n = 3). (C) Analysis of BRCA2 knockdown by Western blotting and real-time RT-PCR.