Table 1.
Clinical, imaging, and pathological findings at histological diagnosis in the 33 patients with diffuse low-grade glioma
| PatientNumber | Sex | Age(years) | KPS | Tumor location | Side | Tumor volume(cm3) | MTD(mm) | Tumor midlinecrossing | IDHexpression | p53expression | Proliferationindex | Spontaneous VDE(mm/year) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | F | 36 | 90 | Temporo-insular | L | 56.6 | 48.4 | No | – | – | – | – |
| 2 | M | 43 | 90 | Frontal | R | 60.6 | 49.5 | No | No | No | High | 2.3 |
| 3 | M | 35 | 100 | Frontal | R | 19.2 | 33.7 | No | – | – | Low | 0.7 |
| 4 | M | 32 | 70 | Fronto-parietal | L | 121.2 | 62.3 | No | Yes | Yes | High | 15.7 |
| 5 | F | 53 | 80 | Frontal | R | 52.6 | 47.2 | No | Yes | No | High | 5.8 |
| 6 | F | 54 | 70 | Cingular | L | 17.8 | 32.9 | No | – | No | Low | 1.8 |
| 7 | M | 66 | 90 | Frontal | R | 6.5 | 23.6 | No | No | Yes | High | 4.5 |
| 8 | M | 30 | 80 | Frontal | R | 35.6 | 41.5 | No | Yes | Yes | Low | 1.9 |
| 9 | M | 39 | 90 | Fronto-temporo-insular | R | 117.7 | 61.8 | Yes | Yes | Yes | Low | – |
| 10 | M | 29 | 90 | Frontal | R | 25.5 | 37.1 | No | Yes | Yes | Low | 3.7 |
| 11 | F | 41 | 90 | Temporo-insular | L | 56.1 | 48.2 | No | Yes | No | Low | 5.0 |
| 12 | M | 40 | 90 | Temporal | L | 15.4 | 31.4 | No | Yes | – | High | – |
| 13 | M | 32 | 90 | Parietal | R | 66.3 | 51.0 | No | – | – | Low | 1.8 |
| 14 | M | 40 | 100 | Temporo-insular | R | 50.7 | 46.6 | No | No | Yes | High | – |
| 15 | M | 26 | 90 | Parieto-temporo-insular | R | 69.7 | 51.8 | No | Yes | Yes | High | – |
| 16 | M | 42 | 90 | Frontal | L | 7.1 | 24.2 | No | Yes | Yes | Low | 5.0 |
| 17 | F | 32 | 90 | Fronto-temporo- insular | L | 273.6 | 81.8 | No | – | Yes | Low | – |
| 18 | M | 23 | 70 | Fronto-cingulo-callosal | R | 10.0 | 27.1 | Yes | Yes | Yes | – | 11.3 |
| 19 | M | 39 | 90 | Fronto-temporo-insular | R | 55.5 | 48.1 | No | Yes | Yes | Low | – |
| 20 | M | 43 | 90 | Parietal | R | 27.1 | 37.8 | No | Yes | Yes | Low | 5.7 |
| 21 | M | 50 | 90 | Temporo-insular | L | 80.5 | 54.4 | No | – | – | High | 6.4 |
| 22 | M | 25 | 100 | Frontal | R | 48.0 | 45.8 | No | Yes | No | Low | – |
| 23 | M | 36 | 90 | Fronto-temporo-insular | L | 110.2 | 60.4 | No | Yes | Yes | Low | 2.9 |
| 24 | F | 31 | 100 | Fronto-parietal | R | 62.4 | 50.0 | No | Yes | Yes | Low | 4.3 |
| 25 | F | 44 | 80 | Temporal | L | 43.1 | 44.2 | No | Yes | No | High | – |
| 26 | F | 42 | 100 | Frontal | R | 27.4 | 38.0 | Yes | Yes | Yes | Low | 15.0 |
| 27 | F | 32 | 100 | Fronto-insular | R | 85.3 | 66.6 | No | Yes | – | High | – |
| 28 | M | 64 | 80 | Parietal | L | 32.5 | 40.2 | No | No | – | High | 16.90 |
| 29 | M | 50 | 90 | Fronto-insular | R | 81.7 | 54.7 | No | Yes | No | Low | – |
| 30 | M | 30 | 90 | Parietal | L | 23.4 | 36.1 | No | Yes | – | High | 0.6 |
| 31 | F | 40 | 90 | Temporo-occipital | L | 34.6 | 41.1 | No | Yes | No | Low | – |
| 32 | M | 48 | 100 | Temporo-parieto-cingular | L | 147.9 | 66.6 | Yes | Yes | No | High | – |
| 33 | F | 41 | 100 | Temporo-parietal | R | 112.3 | 60.8 | No | Yes | Yes | Low | – |
Abbreviations: KPS, Karnofsky performance status; MTD, mean tumor diameter; IDH, isocitrate dehydrogenase; VDE, velocity of diametric expansion.