Table 3.

Cox’s proportional hazards analysis

Factors	Hazard ratio	95% CI	P value
		upper-lower
Depth of invasion
T2/T1	7.850	1.454-42.390	0.017
T3/T1	23.200	4.733-113.716	0.000
T4/T1	65.052	10.830-390.730	< 0.0001
Lymph node metastasis
N1/N0	1.856	0.865-3.982	0.112
N2/N0	3.520	1.597-7.758	0.002
N3/N0	7.227	3.349-15.596	< 0.0001
Desmoplastic reaction
Mild/none	3.663	1.272-10.638	0.016
Moderate/none	3.623	1.304-10.101	0.014
Marked/none	4.926	1.590-15.152	0.006
CCL-7			0.801
CCL-8			0.620
CCL-21			0.084

CCL: Chemokine ligand.