Table 3.
Factors associated with coronary heart disease in the present cohort1
| Factors | Hazard ratio (95% CI) | P value |
| Male | 0.76 (0.33-1.79) | 0.54 |
| BMI at enrollment (compared with 22 < BMI < 25) (kg/m2) | ||
| BMI ≤ 18.5 | 0.87 (0.18-4.36) | 0.87 |
| 18.5 < BMI ≤ 22 | 1.86 (0.80-4.36) | 0.15 |
| 25 < BMI ≤ 30 | 1.60 (0.75-3.41) | 0.23 |
| HbA1c | 1.19 (1.02-1.38) | 0.029 |
| Systolic blood pressure | 1.04 (1.02-1.06) | 0.0005 |
| Diastolic blood pressure | 0.96 (0.92-1.01) | 0.06 |
| Total cholesterol | 0.99 (0.95-1.04) | 0.79 |
| HDL-cholesterol | 0.97 (0.92-1.02) | 0.21 |
| LDL-cholesterol | 1.01 (0.97-1.05) | 0.77 |
| Triglyceride | 1.00 (0.99-1.01) | 0.86 |
| Diabetic retinopathy | 2.38 (1.28-4.43) | 0.006 |
| Proteinuria | 0.71 (0.34-1.48) | 0.36 |
| ApoE phenotype (compared with apoE3 homozygosity) | ||
| ApoE2 | 0.93 (0.31-2.80) | 0.89 |
| ApoE4 | 0.69 (0.18-1.79) | 0.58 |
1Multivariate Cox proportional hazard analysis adjusted with age and smoking status at enrollment. ApoE: Apolipoprotein E gene; HDL: High density lipoprotein; LDL: Low density lipoprotein.