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. 2012 Mar 21;7(3):e33312. doi: 10.1371/journal.pone.0033312

Figure 1. T. gondii infection inhibited spontaneous neuronal degeneration in Tg2576 AD mice.

Figure 1

Histological changes in the hippocampal formation of Tg2576 AD mice were observed by H&E staining, and changes in T. gondii-infected (B; ME49) and uninfected mice were compared (A; PBS). Neuronal death, represented by eosinophilic neurons (PBS, ×100), was remarkably lower in the hippocampal region of infected Tg2576 mice (B; ME49) than in Tg2576 mice (A; PBS), which showed spontaneous neuronal degeneration (×100). Scale bar = 100 µm. Results are represented as percentages of degenerative cells among all cells in dentate gyrus of hippocampal formation (C).