Figure 2. Cytokine profile of LACK_158–175 specific CD4⁺ T cells.

Cells were obtained from spleens of naïve control mice or PR8-LACK_ins and PR8-LACK_rep mice on day 10 following priming. Cells were cultured in the presence of LACK_158–173 peptide for 72 h, and culture supernatants were analysed for cytokine production by capture ELISA. Mean, pooled data ± SD are plotted (n = 3, n refers to number of mice) *p = 0.001, **p = 0.003, ***p = 0.009, ****p = 0.01, ND – below detection level.