Table 2. Physico-chemical characterization of nanoparticle formulation.
Formulation | Size (nm)a | Zeta Potential (mV)b | Polydispersity Index | Entrapment efficiency (%)c |
Nut-NP | 226±7.3 | −18.4±0.57 | 0.14±0.008 | 65±4.3 |
Fol-Nut-NPs | 234±6.5 | −16.8±0.8 | 0.11±0.005 | 63±1.4 |
Cur-NP | 227±5.3 | −17.9±0.37 | 0.18±0.007 | 86±5.8 |
Fol-Cur-NPs | 236±5.5 | −16.2±0.49 | 0.12±0.009 | 77±2.1 |
Nut-Cur-NP | 229±6.3 | −18.9±0.87 | 0.14±0.005 | 64±3.2 (nutlin), 85±3.3 (curcumin) |
Fol-Nut-Cur-NPs | 235±4.6 | −15.9±0.59 | 0.16±0.008 | 63±1.2 (nutlin) 84±2.4 (curcumin) |
Size in nm was measured by Zetasizer.
Zeta potential in mV was measured by Zetasizer.
Polydispersity Index was measured by Zetasizer.
Entrapment efficiency of different drugs were measured by HPLC.
Size was measured by DLS using a Zetasizer. The surface charge was also measured by Zetasizer.