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. 2012 Jan;18(1):48–56. doi: 10.3201/eid1801.101969

Table 4. Estimates of the reproduction number across influenza pandemic locations in the Americas , 1918–19*.

Location, north to south Time of pandemic wave R estimate
Source
3-d serial interval 6-d serial interval
45 US cities† 1918 autumn† 1.7–1.8 2.5–3.3 (2,22)
Toluca 1918 spring 1.6–1.8 2.4–3.1 (3)
Toluca 1918 autumn 2.0–2.5 3.2–6.1 (3)
Mexico City 1918 spring 1.3–1.3 1.7–1.8 (3)
Mexico City 1918 autumn 1.3–1.3 1.6–1.7 (3)
Boyacá, Colombia 1918 Oct–Nov 1.4–1.5 1.8–2.3 This study
Lima, Peru 1918 Nov–1919 Feb 1.3–1.4 1.6–2.0 (4)

*Values are based on a range of estimates provided by considering different distributions of the generation interval (exponentially distributed latent and infectious periods or fixed generation interval). R, reproduction number.
†R estimates are based on the mean of the initial growth rates across 45 US cities.