SUMOylation and neuronal function. SUMOylation has been reported to regulate various aspects of neuronal function and morphology. Shown are a number of these processes, along with identified SUMO substrates involved in them. See text for more details. Abbreviations: MEF2A, myocyte enhancer factor 2A; CASK, calcium/calmodulin-dependent serine kinase; CB1, cannabinoid receptor 1; mGluR, metabotropic glutamate receptor; Drp1, dynamin-related protein 1.